Quantitative diffuse reflectance and fluorescence spectroscopy: tool to monitor tumor physiology in vivo
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چکیده
منابع مشابه
Quantitative diffuse reflectance and fluorescence spectroscopy: tool to monitor tumor physiology in vivo.
This study demonstrates the use of optical spectroscopy for monitoring tumor oxygenation and metabolism in response to hyperoxic gas breathing. Hemoglobin saturation and redox ratio were quantified for a set of 14 and 9 mice, respectively, measured at baseline and during carbogen breathing (95% O(2), 5% CO(2)). In particular, significant increases in hemoglobin saturation and fluorescence redox...
متن کاملQuantitative Diffuse Reflectance Spectroscopy
In the field of biomedical optics, diffuse reflectance spectroscopy (DRS) is a frequently used technique for obtaining information about the optical properties of the medium under investigation. The method utilizes spectral difference between incident and backscattered light intensity for quantifying the underlying absorption and scattering processes that affects the light-medium interaction. I...
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Intramyocardial oxygen transport was assessed during open-chest surgery in calves by diffuse reflectance spectroscopy using a small intramuscular fiber-optic probe. The sum of hemo- and myoglobin tissue fraction and oxygen saturation, the tissue fraction and oxidation of cytochrome aa3, and the tissue fraction of methemoglobin were estimated using a calibrated empirical light transport model. I...
متن کاملDiffuse Reflectance Spectroscopy
The appearance of a soil results from the interaction of its different constituents with incident light. Color and various other attributes of the appearance of soil are highly sensitive to the nature, proportion, particle size and morphology, and spatial association of its mineral and organic components. In fact, color has been used for more than 75 yr to obtain information about these soil pr...
متن کاملIntrinsic fluorescence and diffuse reflectance spectroscopy identify superficial foam cells in coronary plaques prone to erosion.
OBJECTIVE Foam cells perform critical functions in atherosclerosis. We hypothesize that coronary segments with superficial foam cells (SFCs) situated in a region of interest with a depth of 200 mum can be identified using intrinsic fluorescence spectroscopy (IFS) and diffuse reflectance spectroscopy (DRS). This is a key step in our ongoing program to develop a spectroscopic technique for real-t...
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ژورنال
عنوان ژورنال: Journal of Biomedical Optics
سال: 2009
ISSN: 1083-3668
DOI: 10.1117/1.3103586